Author: Jenny Lu

PharmGKB: Pharmacogenetic Database

PharmGKB is a publicly available internet research tool that provides information about how genetic variation among individuals contributes to differences in reactions to drugs. Developed by Stanford University and funded by the National Institutes of Health (NIH), PharmGKB is the largest…

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Three new conditions now available in TreatGxplus

The team at GenXys is excited to announce that Gastroesophageal Reflux Disease, H. pylori Eradication and Dyspepsia/Peptic Ulcer Disease are now covered by TreatGxPlus (pharmacogenetic test and decision support system).   H. pylori Eradication   Helicobacter pylori is a bacterium that…

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Metformin pharmacogenetics: The most up to date evidence does not support clinical use

The most up to date evidence does not support the use of SLC47A2 variants to predict glycemic response to metformin in diabetes Type 2 diabetes Type 2 diabetes is a chronic condition that affects the way the body metabolizes glucose (sugar)…

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New conditions now available in TreatGxPlus

The team at Genxys is excited to announce that Post-Myocardial Infarction (Heart Attack) and Smoking Cessation are now covered in TreatGxPlus (pharmacogenetic test and decision support system). Post-Myocardial Infarction (Heart Attack) A myocardial infarction (MI) is also known as a heart…

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How are the genes in the TreatGxPlus pharmacogenetic test selected?

The TreatGxPlus pharmacogenetic test was developed using an evidence-based approach, following a rigorous review process of scientific studies and professional guidelines. This process allows us to select genetic variants with strong evidence for a significant clinical outcome indicating a change in…

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Lithium pharmacogenetics: Low levels of evidence

Genetic differences can cause a medication to work effectively in one person while failing to help, or even causing harm in another person. Pharmacogenetic testing detects these differences and can prevent adverse drug reactions (ADRs) and ineffective treatments. Pharmacogenomics is an…

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Generation Genome – Department of Health England, CMO calls for the development and adoption of intelligent decision support systems in routine medical practice

Developments in information technology is vital to integrate genomic knowledge into electronic prescribing systems and facilitate adoption into practice The Chief Medical Officer (CMO) of the Department of Health England, Professor Dame Sally Davies, has called for making genomic testing part…

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Clinical decision support systems (CDSS): improving healthcare by linking observations with knowledge to influence health choices by clinicians

Clinical decision support systems provide healthcare professionals assistance with clinical decision-making tasks at the point of care Clinical decision support systems (CDSS) achieve clinical advice for patient care based on multiple items of patient data and knowledge management. Clinicians interact with…

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Combating Alert Fatigue in Healthcare

Alerts intended to improve patient care result in a paradoxical increase risk of harm Most healthcare technologies include automated alert systems so clinicians can prevent or act in unsafe situations. However, healthcare professionals are flooded with alerts from electronic health record…

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GenXys is proud to announce our partnership with LifeLabs: Bringing personalized medicine to Canadians

Pharmacogenetic testing and a smart online tool help doctors prescribe the right medications at the right dose from diagnosis for Canadians    Prescribing the right medication for an individual is complex and the wrong medication or an incorrect dose can have…

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